Influenza A Virus M2 Protein Selectivity and Permeability of Ammonium Ions at Varying pH

Authors

Jared Kevin Pearson, Brigham Young University
David D. Busath, Brigham Young University

Keywords

influenza A, M2 protein, ammonium ions, pH

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

The M2 protein inside the Influenza A virus capsid is vital to the virus’ replication. When the virus enters a cell, the M2 protein forms ion channels that allow the viral RNA to dissociate from stabilizing proteins, enter the host cell nucleus, and replicate. Blocking the formation of these ion channels, or disabling M2 protein ion transport therefore is an important area of research; inactivating the channel will prevent Influenza A replication.

Recommended Citation

Pearson, Jared Kevin and Busath, David D. (2013) "Influenza A Virus M2 Protein Selectivity and Permeability of Ammonium Ions at Varying pH," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 1406.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/1406