The Effects during Embryogenesis and Tumorigenesis of Dominant-Active Beta Catenin in Wnt Signaling

Authors

Melissa Schmidt, Brigham Young University
Dr. Jeffery Richard Barrow, Brigham Young University

Keywords

embryogenesis, tumorigenesis, Wnt signaling

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

Cell communication is crucial in multiceullar organisms. Cells have therefore devised signaling pathways for intracellular communication. One of these is the Wnt signaling pathway. Wnt signaling plays an important role in cell fate decisions during embryogenesis. In the adult, Wnt signaling has been hypothesized to be essential in the maintenance of adult gut, blood, and skin tissues. Interestingly, aberrant Wnt signaling has been found to be the primary defect in all colon cancers and to be the cause of other tumors such as hepatocellular carcinoma (HCC).

Recommended Citation

Schmidt, Melissa and Barrow, Dr. Jeffery Richard (2013) "The Effects during Embryogenesis and Tumorigenesis of Dominant-Active Beta Catenin in Wnt Signaling," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 1399.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/1399