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Journal of Undergraduate Research

Keywords

FOXO1a, type 2 diabetes, Thioredoxin-interacting protein

College

Life Sciences

Department

Nutrition, Dietetics, and Food Science

Abstract

Type 2 Diabetes Mellitus is a public health concern for the United States and is becoming a global health crisis. The hallmark of type 2 diabetes is high blood sugar, which leads to a host of other health issues. In healthy subjects, insulin acts as a signal to increase uptake of glucose from the blood stream into skeletal muscle. However, with the onset of diabetes skeletal muscle becomes resistant to insulin signaling. One of the many factors involved in skeletal muscle insulin resistance is Forkhead Box Protein 1a (FOXO1a) [1].

Included in

Nutrition Commons

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