Quantification of Kaposi’s Sarcoma Herpesvirus Gene Expression in Infected Humanized Mice

Authors

Mark Rowan, Brigham Young University
Dr. Bradford K. Berges, Brigham Young University

Keywords

Kaposi’s Sarcoma Herpesvirus, KSHV, infected humanized mice

College

Life Sciences

Department

Microbiology and Molecular Biology

Abstract

Kaposi’s Sarcoma Herpesvirus (KSHV) is a prevalent disease around the world. Some Sub- Saharan African countries have infection levels as high as 40 percent. Usually the effects of this disease are not fatal unless the infected person has already been infected with HIV or has some other immunodeficiency. If both of these problems exist, deadly cancers can form within the infected person1. Studies have shown that people with HIV are 200,000 times more likely to have Kaposi’s sarcoma (a cancer caused by KSHV) than those not infected. Until now, no competent animal model existed to study KSHV pathogenesis.

Recommended Citation

Rowan, Mark and Berges, Dr. Bradford K. (2013) "Quantification of Kaposi’s Sarcoma Herpesvirus Gene Expression in Infected Humanized Mice," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 1323.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/1323