Journal of Undergraduate Research
Keywords
estrogen receptor, ER, breast cancer, steroid hormone
College
Life Sciences
Department
Microbiology and Molecular Biology
Abstract
Estrogen is a steroid hormone that acts in the body in both beneficial and detrimental ways. It plays a crucial role in many human processes including coagulation, bone formation, and development of sexual organs. However, estrogen is also associated with the proliferation of breast cancer. Estrogen activates the estrogen receptor (ER), a ligand-dependent transcription factor that regulates gene expression by binding to specific DNA elements and promoting or repressing transcription.
Recommended Citation
Harris, Victoria and Lin, Dr. Chin-Yo
(2013)
"Estrogen and Breast Cancer: Understanding the Complex Interaction One Gene at a Time,"
Journal of Undergraduate Research: Vol. 2013:
Iss.
1, Article 1260.
Available at:
https://scholarsarchive.byu.edu/jur/vol2013/iss1/1260