Thymidine Kinase 1 Immunostaining for Marking the Progression of Skin Cancer

Authors

Kendal Jensen, Brigham Young University
Dr. Kim O'Neill, Brigham Young University

Keywords

thymidine Kinase 1, TK1, immunostaining, skin cancer

College

Life Sciences

Department

Microbiology and Molecular Biology

Abstract

Each year in the United States there are over one million cases of nonmelanoma skin cancer. Detection of metastatic skin cancer requires skill and careful consideration of clinical and histologic features. An accurate and specific stain for early, definitive diagnosis of metastatic skin cancer would be a useful tool for clinicians. Investigations using antibodies against tumor-specific antigens (TSAs) as prognostic indicators in cancer are ongoing. A novel TSA, Thymidine Kinase 1 (TK1) has been discovered for a variety of solid tumors. This last year in Kim O’Neill’s lab I investigated the use of an antibody against TK1 for use in diagnosis of skin cancer.

Recommended Citation

Jensen, Kendal and O'Neill, Dr. Kim (2013) "Thymidine Kinase 1 Immunostaining for Marking the Progression of Skin Cancer," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 1257.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/1257