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Journal of Undergraduate Research

Keywords

thymidine kinase-1, TK-1, UV induced B lymphocytes, cell death

College

Life Sciences

Department

Microbiology and Molecular Biology

Abstract

The normal life of a eukaryotic cell involves a dynamic struggle between survival and death. When a cell is no longer capable of living, certain pathways are initiated for natural cell death. These “programmed cell deaths” transpire in predictable patterns, and are regulated by many proteins and signals that either activate or inactivate the cell death pathways. Changes in the various homeostatic molecules initiate the apoptotic pathway. However, there are other agents within the cell that regulate these apoptotic triggers. Tumors can arise when these regulatory proteins are mutated, inactivated, or ignored, resulting in the aggressive replicating nature of tumor cells.

Included in

Microbiology Commons

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