Journal of Undergraduate Research
Keywords
human vestibular schwannoma, VS, xenograft model, SCID mice
College
Life Sciences
Department
Microbiology and Molecular Biology
Abstract
Vestibular Schwannoma (VS) is a benign, slow growing tumor that arises from the myelin sheath of the vestibular nerve (cranial nerve VIII). The myelin sheath is composed of flat, layered cells known as Schwann cells, which serve to insulate nerve fibers. It is increased proliferation of these Schwann cells which leads to VS tumor growth. As VS tumors grow, they place increasing pressure on cranial nerve VIII, causing hearing loss, tinnitus (ringing in the ear), and balance dysfunction. Eventually VS tumors may lead to brainstem compression and even death.1
Recommended Citation
Welling, John and O'Neil, Dr. Kim
(2013)
"Development of a Novel Human Vestibular Schwannoma Xenograft Model in SCID Mice,"
Journal of Undergraduate Research: Vol. 2013:
Iss.
1, Article 1217.
Available at:
https://scholarsarchive.byu.edu/jur/vol2013/iss1/1217