Investigation into the Mechanisms Associated with Angiogenesis and Metastasis

Authors

Rachelle R. Olsen, Brigham Young University
Dr. Kim L. O'Neill, Brigham Young University

Keywords

angiogenesis, metastasis, human malignancies, chick embryo

College

Life Sciences

Department

Microbiology and Molecular Biology

Abstract

Angiogenesis, the development and differentiation of new blood vessels from pre-existing vasculature, is tightly controlled during physiological processes including wound healing, growth, and development. Angiogenesis is also associated with several human malignancies including arthritis, psoriasis, and cancer. Angiogenesis, which provides a source of nutrients and a waste outlet for biological products, is absolutely required for a tumor to grow larger than a few millimeters in size. Blood vessels formed by angiogenesis are young and immature and can facilitate metastasis, the spread and subsequent growth of primary tumor cells to distal body sites.

Recommended Citation

Olsen, Rachelle R. and O'Neill, Dr. Kim L. (2013) "Investigation into the Mechanisms Associated with Angiogenesis and Metastasis," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 1202.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/1202