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Journal of Undergraduate Research

Keywords

functional comparisons, LTA, TNF-a Gene protein

College

Life Sciences

Department

Biology

Abstract

TNF-a is a cytokine released by activated macrophages and lymphotoxin alpha (LTA) is a cytokine released by activated lymphocytes. Both proteins act as modulators of the immune response and competitively bind to the same protein receptors TNFR-1 and TNFR-2. The protein sequences themselves are 35% identical and 50% homologous to one another.

Included in

Biology Commons

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