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Cognitive therapy targets, nAChr mRNA
We quantified mRNA subunit expression in the CA1 rat hippocampus. The a3 and B2 nAChR subunits are the highest expressed mRNA subunits while the a4 is the least. Current nAChR targeted cognitive therapies focus on the a4B2 and a7 nAChRs. These results provide a new avenue in cognitive therapies by targeting a3 containing nAChRs.
The Annual Mary Lou Fulton Mentored Research Conference showcases some of the best student research from the College of Family, Home, and Social Sciences. The mentored learning program encourages undergraduate students to participate in hands-on and practical research under the direction of a faculty member. Students create these posters as an aide in presenting the results of their research to the public, faculty, and their peers.
BYU ScholarsArchive Citation
Thompson, Spencer; Wright, Maxwell; Grant, Taylor; Vance, Brady; Ahern, Nicholas; Ogden, Jeffrey; Drecketts, Romaine; Pugh, David; Fisher, Zach; Werner, Sara; Fowlers, Jaron; Klienstuber, Bradley; Burgon, Richard; Sego, Ashley; Jackson, Doris; and Sudweeks, Sterling N., "Identifying Novel Cognitive Therapy Targets: Expression of nAChR mRNA in Rat Hippocampal Interneurons" (2017). FHSS Mentored Research Conference. 312.
Family, Home, and Social Sciences
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