phase transitions, gene delivery, ultrasound
A computer model was written that simulates the transformation of a nanoemulsion droplet to a gas bubble by the application of ultrasound. Experimentally such a technique could be used to enhance non-viral gene transfection beyond the boundary of the endothelial lining of the circulatory system, particularly in tumors exhibiting enhanced permeation and retention of nanoparticles.
Original Publication Citation
Pitt, W.G., Singh, R., and Husseini, G.A. "Modeling Phase Transitions of Nanoemulsions for Ultrasonic Gene Delivery", Annual Meeting of the Controlled Release Society, 35, 692, New York, NY, July 13-16, 28
BYU ScholarsArchive Citation
Husseini, Ghaleb A.; Pitt, William G.; and Singh, Ram, "Modeling Phase Transitions of Nanoemulsion for Ultrasonic Gene Delivery" (2008). Faculty Publications. 57.
Ira A. Fulton College of Engineering and Technology
© 2008 William G. Pitt et al.
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