Understanding the Molecular Phenotype of Obesity-Associated Clear Cell Renal Cell Carcinoma in the Context of the Obesity Paradox

Authors

Elisa McRae, Brigham Young University - ProvoFollow
Joseph Wride, Brigham Young University - Provo
Carter Norton, Brigham Young University - Provo
Matthew Tufts, Brigham Young University - Provo
Connor Peterson, Brigham Young University - Provo
Badí Quinteros, Brigham Young University - Provo
Olivia Rodriguez, Brigham Young University - Provo
Alejandro Sanchez, Brigham Young University - Provo

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Keywords

renal cancer, obesity, genetic, biological marker, obesity paradox

Abstract

• Clear cell renal cell carcinoma (ccRCC) is the most prevalent histologic subtype of renal cell carcinoma in the US, constituting 85% of cases, with an estimated 69,000 new cases in 2023.
• Obese patients have an elevated risk of developing ccRCC.
• Despite the increased risk, obese patients with ccRCC paradoxically exhibit better outcomes compared to normal-weight patients, known as the “obesity paradox.”
• Understanding the molecular phenotype of obesity-associated ccRCC is the focus of this study.

BYU ScholarsArchive Citation

McRae, Elisa; Wride, Joseph; Norton, Carter; Tufts, Matthew; Peterson, Connor; Quinteros, Badí; Rodriguez, Olivia; and Sanchez, Alejandro, "Understanding the Molecular Phenotype of Obesity-Associated Clear Cell Renal Cell Carcinoma in the Context of the Obesity Paradox" (2024). Library/Life Sciences Undergraduate Poster Competition 2024. 69.
https://scholarsarchive.byu.edu/library_studentposters_2024/69

Document Type

Poster

Publication Date

2024-03-21

Language

English

College

Life Sciences

Department

Biology

University Standing at Time of Publication

Senior

Copyright Use Information

https://lib.byu.edu/about/copyright/