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Keywords
Antibody-Drug Conjugates; Synovial Sarcoma
Abstract
Synovial sarcomas (SS) are rare soft tissue cancers that are found beside bone in children and adolescents. Currently, the prognosis for these diseases are low, as diagnostic and treatment options are limited due to the rarity of the disease. With high rates of metastasis, treatment options for these diseases become further limited to primarily radiation and chemotherapies. These therapies have limited specificity in their mechanisms, causing severe side effects in patients. This work examined alternative options for synovial sarcoma theranostic approaches, specifically using immunoconjugates for Oncostatin M Receptors (OSMR). This receptor was chosen due to the high rate of expression of Oncostatin M in many cancers, including synovial sarcoma. It is involved in cancer proliferation and metastasis, making it a good target for treatment.
BYU ScholarsArchive Citation
Burr, Machenzie; Barrott, Jared; Okojie, Jeffrey; Anderson, DeLaney; Worley, Peyton; Davis, Jack; Kearns, Bridger; and I'anson-Holton, Melanie, "Theranostic Approaches to Treat Synovial Sarcoma" (2024). Library/Life Sciences Undergraduate Poster Competition 2024. 12.
https://scholarsarchive.byu.edu/library_studentposters_2024/12
Document Type
Poster
Publication Date
2024-03-21
Language
English
College
Life Sciences
Department
Cell Biology and Physiology
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