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Keywords

nachr, nicotinic, hippocampus, a3b2, alpha-3 beta-2, interneuron, dose-response, electrophysiology, stoichiometry

Abstract

We have identified two subtypes of the novel a3b2 nicotinic acetylcholine receptor (nAChR) found within interneurons of the hippocampus. This novel receptor may be a valuable pharmacological target in drug development for disease such as Alzheimer’s disease (AD) which is largely characterized by degeneration of the hippocampus.

Description

The Annual Mary Lou Fulton Mentored Research Conference showcases some of the best student research from the College of Family, Home, and Social Sciences. The mentored learning program encourages undergraduate students to participate in hands-on and practical research under the direction of a faculty member. Students create these posters as an aide in presenting the results of their research to the public, faculty, and their peers.

Document Type

Poster

Publication Date

2016-04-07

Language

English

College

Family, Home, and Social Sciences

Department

Neuroscience

University Standing at Time of Publication

Graduate Student

Novel Pharmacological Target: Characterization of a3b2 nAChRs expressed in Xenopus Laevis Oocytes

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