Title
Novel Pharmacological Target: Characterization of a3b2 nAChRs expressed in Xenopus Laevis Oocytes
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Keywords
nachr, nicotinic, hippocampus, a3b2, alpha-3 beta-2, interneuron, dose-response, electrophysiology, stoichiometry
Abstract
We have identified two subtypes of the novel a3b2 nicotinic acetylcholine receptor (nAChR) found within interneurons of the hippocampus. This novel receptor may be a valuable pharmacological target in drug development for disease such as Alzheimer’s disease (AD) which is largely characterized by degeneration of the hippocampus.
Description
The Annual Mary Lou Fulton Mentored Research Conference showcases some of the best student research from the College of Family, Home, and Social Sciences. The mentored learning program encourages undergraduate students to participate in hands-on and practical research under the direction of a faculty member. Students create these posters as an aide in presenting the results of their research to the public, faculty, and their peers.
BYU ScholarsArchive Citation
Jackson, Doris; Hall, Marcel; Kolb, J.; Todd, B. Jr.; Pugh, D.; Vance, B.; Klienstuber, B.; Drecketts, R.; and Sudweeks, S. N., "Novel Pharmacological Target: Characterization of a3b2 nAChRs expressed in Xenopus Laevis Oocytes" (2016). FHSS Mentored Research Conference. 295.
https://scholarsarchive.byu.edu/fhssconference_studentpub/295
Document Type
Poster
Publication Date
2016-04-07
Language
English
College
Family, Home, and Social Sciences
Department
Neuroscience
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