Keywords
phase transitions, gene delivery, ultrasound
Abstract
A computer model was written that simulates the transformation of a nanoemulsion droplet to a gas bubble by the application of ultrasound. Experimentally such a technique could be used to enhance non-viral gene transfection beyond the boundary of the endothelial lining of the circulatory system, particularly in tumors exhibiting enhanced permeation and retention of nanoparticles.
Original Publication Citation
Pitt, W.G., Singh, R., and Husseini, G.A. "Modeling Phase Transitions of Nanoemulsions for Ultrasonic Gene Delivery", Annual Meeting of the Controlled Release Society, 35, 692, New York, NY, July 13-16, 28
BYU ScholarsArchive Citation
Husseini, Ghaleb A.; Pitt, William G.; and Singh, Ram, "Modeling Phase Transitions of Nanoemulsion for Ultrasonic Gene Delivery" (2008). Faculty Publications. 57.
https://scholarsarchive.byu.edu/facpub/57
Document Type
Poster
Publication Date
2008-07-13
Permanent URL
http://hdl.lib.byu.edu/1877/2130
Language
English
College
Ira A. Fulton College of Engineering and Technology
Department
Chemical Engineering
Copyright Status
© 2008 William G. Pitt et al.
Copyright Use Information
http://lib.byu.edu/about/copyright/